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Project leader

Pietro Panei Paediatrician, Epidemiologist

Project staff

Description of the organisation

  The Istituto Superiore di Sanità (ISS) is the leading technical and scientific public body of the Italian National Health Service. Its activities include research, control, training and consultation in the interest of public health protection.

Department of Therapeutic Research and Medicines Evaluation:The mission of the Department is: to contribute to public health by controlling the quality, efficacy and safety of drugs and through research into new drugs and treatments for human diseases.
The research activities of the Department, which are carried out in cooperation with other Departments of the Institute, universities, the Scientific Institutes for Research and Care (IRCCS) and other national and international research centres, cover several aspects of pharmacological research, including the synthesis of new compounds and preclinical studies of their mechanisms of action and the coordination of large-scale national and international multicentre clinical trials. Specific areas of involvement include the use of drugs in paediatric patients, cardiovascular diseases, metabolic and endocrine diseases, aging-related conditions, neurological and neurodegenerative disorders, tumours, viral diseases such as HIV/AIDS, and drug-related conditions such as addiction, drug resistance and practice of doping in sport.
The Department is also actively engaged in innovative sectors of modern drug research, such as molecular pharmacology, pharmacokinetics and pharmacogenetics. The control activities of the Department range from ascertaining the chemical purity and efficacy of proprietary and generic drugs to the evaluation of preclinical safety, the monitoring of phase I trials of new drugs and innovative therapies, the technical and scientific examination of applications for licences at national and European level, the monitoring of new drugs after placement on the market and of drug-related adverse effects, and the dissemination of information to promote the proper use of drugs.
 

Previous experience

Profile of staff members

Main tasks in the project