University of Dundee
|School of Medicine, Division of Medical Sciences, Centre for Neuroscience|
|Centre for Child Health, 19|
|DD3 6HH Dundee|
Dr David Coghill
Phone: +44-1382 204004
Fax: +44-1382 346555
|Prof Keith Matthews|
|Dr John Graham|
|Dr Sarah Seth|
|Dr Helen Smith|
Description of the organization:
The University of Dundee is a leading UK institute for medical research. The Dundee Developmental Research Group (DDRG, headed by Dr. David Coghill) specializes in high quality clinical care and research into various child and adolescent neuropsychiatric disorders including ADHD, Conduct Disorder, Depression and Autism Spectrum Disorders. The group’s clinical research is conducted alongside the local Child and Adolescent Mental Health Services with whom they share staff and have strong links. This service receives around 1000 new referrals each year. Drs Coghill, Seth and Graham run the Developmental Disorders Team which is responsible for managing all of the children with ADHD in the region (Current caseload ≈ 800). Clinical trials are conducted within a dedicated children’s clinical trial facility supported by the Scottish Medicines for Children Research Network. As a consequence, research into the efficacy and safety of medication treatment for psychiatric disorders in children and adolescents is on the priority list of research activities.
The UNIVDUN (Coghill) has been involved, as Principle Investigator, in many international collaborations, including multi‐site international medication trials (e.g. Sonuga‐Barke et al 2007), large scale European observational studies (Coghill et al 2006) and neuropsychopharmacological studies (Coghill, Rhodes &, Matthews 2007). The Centre for Neuroscience has experience in working within FP6 Integrated Projects.
Profile of staff members:
David Coghill (MB ChB MRCPsych) is a child and adolescent psychiatrist and a senior lecturer in Child and Adolescent Psychiatry at the University of Dundee and Honorary Consultant Child and Adolescent Psychiatrist in the Tayside Child and Adolescent Mental Health Service. He has been involved in several clinical trials in children and adolescents with ADHD and Conduct Disorder and is currently the global lead investigator for two large multinational clinical trials. He is also active in genetic, neuropsychological, neuropsychopharmacological and quality of life research.
Keith Matthews (MD, PhD) is Professor of Psychiatry, an adult psychiatrist and Deputy Director of the Division of Medical Sciences at the University of Dundee. He is actively involved in neuropsychological and neuropsychopharmacological studies in children and adolescents and in research into treatment resistant depression and Obsessive Compulsive Disorder in adults.
John Graham (MB, ChB, MRCPsych) is a child and adolescent psychiatrist and Clinical Lecturer in Child and Adolescent Psychiatry. His areas of expertise include pharmacogenomics, assessing adverse events and managing ADHD and mood and anxiety disorders. His doctoral thesis is on the pharmacogenomics of methylphenidate.
Sarah Seth (MB ChB MRCPsych) is a child and adolescent psychiatrist and Clinical Lecturer in Child and Adolescent Psychiatry. Her areas of expertise include neuropsychology and medication research in ADHD, Oppositional Defiant Disorder and Conduct Disorder. Her doctoral thesis is on the cognitive endophenotypes of ADHD.
Helen Smith (MB ChB MRCPsych) is a forensic psychiatrist and Clinical Lecturer in Psychiatry. Her areas of expertise are in Conduct Disorder and antisocial behaviours. Her doctoral thesis is on the cognitive endophenotypes of Conduct Disorder.
Main tasks in the project:
This partner is providing co‐leadership (clinical) on the project (Coghill). UNIVDUN will also have lead responsibility for the development and running of the prospective cohort study (WP3). It will also actively contribute to patient recruitment in WP3 to data management in WP4.
The fifth ADDUCE Newsletter is now available!
Here, you can read about the finalisation of the project,
the European Medicines Agency and General Assembly meetings
and the dissemination of the results!
The fourth ADDUCE Newsletter is available!
In this newsletter, you can find some information on the final recruitment status of the 2 main studies:
- the prospective open-label methylphenidate pharmacovigilance study
- the long-term cardiascular effects of methylphenidate use
Also, you can read about the future plans of the project!
More than 1500 children, adolescents and adults across all Europe already took part in our study! Thanks to them, we have already gathered lots of information so we can know a lot more about methylphenidate than ever before!
Did you participate in the ADDUCE studies and are you curious about the latest news on the project?
Here you can find some information!
News for children, April 2015
News for adolescents, April 2015
News for parents, April 2015
The third ADDUCE Newsletter is available!
- the prospective open-label methylphenidate pharmacovigilance study: recruitment status and spin-
- the long-term cardiovascular effects of methylphenidate use: study design and participation
and much more in the ADDUCE Newsletter 3, March 2015
WP3: prospective open-label methylphenidate
- WP8: long-term cardiovascular effects of methylphenidate use
and much more in the ADDUCE Newsletter 2, February 2013
16 - 19 OCTOBER 2016:
4rd EUNETHYDIS International Conference on ADHD, Berlin - Germany
from basis neuroscience to optimised clinical care
17 & 18 APRIL 2016:
ADDUCE Consortium meeting, London - UK
28 - 31 MAY 2015:
5th World Congress on ADHD: from Child to Adult Disorder, Glasgow - Scotland
20 & 21 APRIL 2015:
ADDUCE Consortium meeting, Salina - Italy
21 - 24 MAY 2014:
3rd EUNETHYDIS International Conference on ADHD, Istanbul - Turkey
ADHD and related disorders
19 & 20 MAY 2014:
ADDUCE Consortium meeting, Istanbul - Turkey
3 - 6 OCTOBER 2013:
23rd EUNETHYDIS Network Meeting, Prague Czech Republic
A meeting of the European Network of Hyperkinetic Disorders
6 - 9 JUNE 2013:
4th World Congress on ADHD: from Childhood to Adult Disease, Milan - Italy
4 & 5 JUNE 2013:
ADDUCE Consortium meeting, Milan - Italy
6 & 7 JUNE 2012:
ADDUCE Consortium meeting, Cagliari - Italy
23 MAY 2012:
2nd EUNETHYDIS International Conference on ADHD, Barcelona - Spain